Published onJanuary 21, 2025Do Dietary Supplements Work for Weight Loss? Evidence Review by Ingredientweight-loss-supplementsdietary-supplementsevidence-basedEFSAglucomannancaffeinegreen-teaCLAGarcinia-cambogiaMost weight loss supplements lack credible clinical evidence. A small number of ingredients have meaningful evidence for modest effects. This article grades the evidence for the most commonly used weight loss supplement ingredients.