Zoloft

Explore the complex relationship between Zoloft and weight changes, and discover strategies for managing your weight while on this medication. Learn how to support your metabolism and achieve your health goals.

Zoloft (sertraline) can affect weight in complex ways. This article explains the mechanism, what research says about weight changes on SSRIs, and evidence-based strategies for managing your weight while taking sertraline.

Sertraline (Zoloft) has a more complex relationship with weight than most people realise. Short-term weight loss is common early on; longer-term weight gain is more common with sustained use. Here is what the evidence shows and practical strategies for managing weight while on SSRIs.